Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPGM | P07738 | 3/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HAT1 | O14929 | 3/20 | 0.38 |
| ▸ | EP300 | Q09472 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDH2 | P40926 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24271786 | 0.87 | BPGM (0.58) | BPGMPRKACAROCK1ROCK2ALDH1A1 | |
| SCHEMBL24272071 | 0.85 | BPGM (0.56) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24271936 | 0.84 | BPGM (0.55) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24271803 | 0.84 | BPGM (0.57) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24272266 | 0.82 | BPGM (0.53) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24271808 | 0.82 | BPGM (0.53) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24271932 | 0.81 | BPGM (0.63) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24348971 | 0.80 | BPGM (0.65) | BPGMPRKACAROCK1ROCK2PPARD | |
| SCHEMBL24271922 | 0.79 | BPGM (0.57) | BPGMPRKACAROCK1ROCK2ALDH1A1 | |
| SCHEMBL24348967 | 0.78 | BPGM (0.57) | BPGMPRKACAROCK1ROCK2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348450-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION | 2023-11-02 | — | — | US | disclosed |
| US-20230348450-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION | 2023-11-02 | — | — | US | disclosed |
| WO-2022056447-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION (US) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348450-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | BPGM, PGAM1, PGM2 | BPGM 1/4885PRKACA 2283/4885PRKACG 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.