Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HAT1 | O14929 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24273327 | 0.92 | KDM4E (0.56) | KDM4EHPGDCNR1CNR2POLB | |
| SCHEMBL24273244 | 0.85 | SLC22A12 (0.59) | KDM4EHPGDCNR1CNR2HDAC1 | |
| SCHEMBL24273345 | 0.83 | SLC22A12 (0.52) | KDM4EHPGDCNR1CNR2POLB | |
| SCHEMBL24273317 | 0.82 | TUBB4A (0.53) | KDM4EHPGDCNR1CNR2POLB | |
| SCHEMBL24273071 | 0.81 | LMNA (0.56) | KDM4EHPGDCNR1CNR2POLB | |
| SCHEMBL5441848 | 0.80 | HDAC1 (0.59) | KDM4EHPGDCNR1CNR2HDAC1 | |
| SCHEMBL24273556 | 0.80 | TUBB4A (0.63) | KDM4ECNR1CNR2HDAC1HDAC6 | |
| SCHEMBL24273554 | 0.79 | SMN1; SMN2 (0.62) | KDM4EHPGDCNR1CNR2POLB | |
| SCHEMBL24273587 | 0.78 | KLKB1 (0.49) | KDM4ECNR2POLBHDAC1HDAC6 | |
| SCHEMBL24273387 | 0.76 | POLB (0.61) | KDM4EPOLBHDAC1HAT1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061008-A2 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |