Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319299 | 0.90 | HSD11B1 (0.40) | HSD11B1ALDH1A1LMNASLC6A4GRIN2D | |
| SCHEMBL24273788 | 0.88 | HSD11B1 (0.34) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL24139640 | 0.86 | ALDH1A1 (0.40) | HSD11B1ALDH1A1LMNASLC6A4SLC6A2 | |
| SCHEMBL24139505 | 0.82 | ALDH1A1 (0.44) | HSD11B1ALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL24139057 | 0.81 | LMNA (0.36) | HSD11B1LMNA | |
| SCHEMBL24139381 | 0.79 | CHRM2 (0.37) | HSD11B1LMNASLC6A4SLC6A2MRGPRX1 | |
| SCHEMBL24139233 | 0.78 | HSD11B1 (0.44) | HSD11B1ALDH1A1LMNASLC6A4SLC6A2 | |
| SCHEMBL24138769 | 0.77 | KDM1A (0.34) | ALDH1A1 | |
| SCHEMBL24273869 | 0.76 | GRIN2D (0.32) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24139593 | 0.76 | ALDH1A1 (0.41) | HSD11B1ALDH1A1LMNASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262426-A9 | ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2022-03-17 | — | — | WO | disclosed |