Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 12/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682988 | 0.93 | MMP12 (0.40) | MMP12PSMB8PSMB5PSMB10PSMB2 | |
| SCHEMBL19683070 | 0.93 | MMP12 (0.40) | MMP12PSMB8PSMB5PSMB10PSMB2 | |
| SCHEMBL19683064 | 0.90 | MMP12 (0.42) | MMP12PSMB8PSMB5PSMB10PSMB2 | |
| SCHEMBL23425701 | 0.87 | CTSD (0.37) | PSMB5CACNA1B | |
| SCHEMBL24276205 | 0.86 | CTSD (0.37) | PSMB5CACNA1B | |
| SCHEMBL23425671 | 0.85 | ITGB3 (0.36) | MMP12PSMB5 | |
| SCHEMBL19682984 | 0.84 | GRIA1 (0.45) | MMP12PSMB8 | |
| SCHEMBL19682986 | 0.82 | ITGB3 (0.38) | MMP12PSMB5 | |
| SCHEMBL24942160 | 0.81 | PSMB5 (0.41) | PSMB5 | |
| SCHEMBL19683185 | 0.81 | ITGB3 (0.37) | PSMB8PSMB5PSMB10PSMB2PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464336-B1 | COMPOUNDS | ATHIRA PHARMA INC (US) | 2022-03-16 | — | — | EP | disclosed |