⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217292 | 0.87 | TSHR (0.48) | — | |
| SCHEMBL4737443 | 0.86 | TSHR (0.56) | — | |
| SCHEMBL8799477 | 0.86 | TSHR (0.50) | — | |
| SCHEMBL16371432 | 0.86 | TSHR (0.50) | — | |
| SCHEMBL16371434 | 0.86 | TSHR (0.50) | — | |
| SCHEMBL39539 | 0.85 | — | — | |
| SCHEMBL1912572 | 0.84 | CA12 (0.46) | — | |
| SCHEMBL272758 | 0.83 | LMNA (0.64) | — | |
| SCHEMBL28496533 | 0.83 | TSHR (0.60) | — | |
| SCHEMBL8812283 | 0.81 | LMNA (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385789-B | Synthesis method of methyl 4-oxo-butyrate | 安徽大学 | 2024-06-04 | — | — | CN | claimed |
| CN-116390920-A | Aromatic spirocyclic amide derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-115677491-A | Preparation process of ethyl 4- (ethoxycarbonyl) methoxybutyrate | 武汉市振邦生物科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115385789-A | Synthesis method of methyl 4-oxobutyrate | 安徽大学 | 2022-11-25 | — | — | CN | claimed |
| CN-114539170-A | Hapten and artificial antigen for simultaneously detecting amantadine, olaquindox and chloramphenicol and preparation method and application thereof | 华南农业大学 | 2022-05-27 | — | — | CN | claimed |
| CN-109265341-B | Synthetic method of 5-aminolevulinic acid hydrochloride | 河南大学 | 2022-03-11 | — | — | CN | claimed |
| CN-108975796-B | Method for manufacturing anti-freezing thermal insulation mortar | 广西腾远水泥制品有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-109810037-B | Method for preparing 2-thiobenzenesulfonylmethyl-3-phenyl methyl acrylate compound by tin catalysis | 浙江农林大学暨阳学院 | 2020-10-09 | — | — | CN | claimed |
| US-9573887-B2 | Naphthalene derivative | DAITO CHEMIX CORPORATION (JP) | 2017-02-21 | — | — | US | claimed |
| US-9018409-B2 | Process for functionalization of unsaturated compounds | MEURICE R&D ASBL (BE) | 2015-04-28 | — | — | US | claimed |
| US-5072005-A | Reacting acrolein, carbon monoxide, methanol in presence of palladium catalyst, hydrogen halide and arylarsine promoter | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1991-12-10 | — | — | US | claimed |
| US-5068222-A | Polypeptides for treatment of cancer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | claimed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | claimed |
| EP-0267605-A2 | Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| US-4654435-A | WITH ORGANIC COMPOUNDS HAVING BOTH A CARBOXYL GROUP AND AN ALDEHYDE GROUP | NIPPON ZEON CO., LTD. (JP) | 1987-03-31 | — | — | US | claimed |
| EP-0162877-A1 | Method to titrate enzymes. | FLORK MICHEL (FR) | 1985-12-04 | — | — | EP | claimed |
| WO-1985002404-A1 | NEW PEPTIDE DERIVATIVES, PREPARATION PROCESS THEREOF AND UTILIZATION THEREOF AS BIOLOGICAL REAGENTS | FLORK MICHEL | 1985-06-06 | — | — | WO | claimed |
| US-4420620-A | Preparation of 2-pyrrolidones | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1983-12-13 | — | — | US | claimed |
| US-4419522-A | ANTITUMOR AGENTS | CHINOIN GYOGYSZER VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-12-06 | — | — | US | claimed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | claimed |