Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496533 | 0.88 | TSHR (0.60) | TSHRLMNAKDM4EALDH1A1CA12 | |
| SCHEMBL242764 | 0.86 | — | — | |
| SCHEMBL25187 | 0.83 | TSHR (0.81) | TSHRLMNAKDM4EALDH1A1CA12 | |
| SCHEMBL10481290 | 0.83 | TSHR (0.81) | TSHRLMNAKDM4EALDH1A1CA12 | |
| SCHEMBL14092783 | 0.79 | TSHR (0.65) | TSHRLMNAKDM4EALDH1A1CA12 | |
| SCHEMBL1714308 | 0.78 | ALDH1A1 (0.34) | TSHRALDH1A1MAPTHPGD | |
| SCHEMBL1714217 | 0.78 | ALDH1A1 (0.34) | TSHRALDH1A1MAPTHPGD | |
| SCHEMBL9618343 | 0.78 | HIF1A (0.41) | TSHRLMNAALDH1A1MAPTHPGD | |
| SCHEMBL9820196 | 0.78 | TSHR (0.50) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL28515816 | 0.78 | HDAC6 (0.38) | TSHRLMNAKDM4ECA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3151372-A | — | — | None | — | — | JP | disclosed |
| WO-2008089487-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008089485-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-0473842-B2 | Flavouring composition containing gamma-jasmolactone, the use of such a flavouring composition or gamma-jasmolactone per se for flavouring foodstuffs as well as the flavoured foodstuffs obtained | QUEST INT (NL) | 2003-05-07 | — | — | EP | disclosed |
| US-5783244-A | Flavoring composition containing gamma-jasmolacton | UNILEVER PATENT HOLDINGS B.V. (NL) | 1998-07-21 | — | — | US | disclosed |
| EP-0473842-B1 | Flavouring composition containing gamma-jasmolactone, the use of such a flavouring composition or gamma-jasmolactone per se for flavouring foodstuffs as well as the flavoured foodstuffs obtained | QUEST INT (NL) | 1996-01-03 | — | — | EP | disclosed |
| EP-0473842-A1 | Flavouring composition containing gamma-jasmolactone, the use of such a flavouring composition or gamma-jasmolactone per se for flavouring foodstuffs as well as the flavoured foodstuffs obtained | QUEST INTERNATIONAL B.V. (NL) | 1992-03-11 | — | — | EP | disclosed |
| JP-H03151372-A | PRODUCTION OF GAMMA-JASMOLACTONE | TOYOTAMA KORYO KK | 1991-06-27 | — | — | JP | disclosed |