Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 13/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.61 |
| ▸ | POLB | P06746 | 12/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | MAPT | P10636 | 11/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.61 |
| ▸ | BLM | P54132 | 8/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | APEX1 | P27695 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 3/20 | 0.61 |
| ▸ | PTGES | O14684 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 6/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 8/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 5/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24277912 | 0.84 | MEN1 (0.74) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL26764244 | 0.84 | MEN1 (0.49) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL24277194 | 0.81 | MCL1 (0.80) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL26295896 | 0.78 | MCL1 (0.82) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL20272154 | 0.78 | MEN1 (0.66) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL24277667 | 0.78 | MCL1 (1.00) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14680362 | 0.77 | MEN1 (0.60) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL24277665 | 0.77 | MCL1 (0.80) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL26296124 | 0.76 | MEN1 (1.00) | MCL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL26294556 | 0.76 | MEN1 (0.73) | MCL1MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365540-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-16 | — | — | US | disclosed |
| US-20230365540-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-16 | — | — | US | disclosed |
| WO-2022056068-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | THE REGENTS OF THE UNIVERSITY OFCALIFORNIA (US) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365540-A1 | SMALL MOLECULE INHIBITORS OF ENPP1 | ENPP1, ENPP2, ENPP3 | MCL1 2179/4885MEN1 2065/4885KMT2A 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.