Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | VHL | P40337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039312 | 0.80 | SYK (0.52) | KMT2ASYKL3MBTL1 | |
| SCHEMBL22190015 | 0.78 | GRIA2 (0.54) | ACVR1MCL1 | |
| SCHEMBL30514393 | 0.78 | GRIA2 (0.54) | ACVR1MCL1 | |
| SCHEMBL22190017 | 0.78 | GRIA2 (0.54) | ACVR1MCL1 | |
| SCHEMBL6418674 | 0.73 | AOC3 (0.67) | KMT2ASYK | |
| SCHEMBL1899410 | 0.72 | NPSR1 (0.57) | MEN1KMT2A | |
| SCHEMBL12001184 | 0.72 | ACACB (0.67) | MEN1KMT2A | |
| SCHEMBL13525175 | 0.72 | ACVR1 (0.54) | ACVR1MMP1MMP9ERN1 | |
| SCHEMBL29675855 | 0.72 | KCNB1 (0.55) | SYK | |
| SCHEMBL4012439 | 0.72 | PRKCI (0.49) | MTNR1AACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220088003-A1 | SMALL MOLECULE PROMOTING OSTEOBLAST DIFFERENTIATION | CORNELL UNIVERSITY | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220088003-A1 | SMALL MOLECULE PROMOTING OSTEOBLAST DIFFERENTIATION | BMP2, BMP4, MYADM | NSD2 1947/4885MEN1 3116/4885KMT2A 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.