Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439957 | 0.80 | TGFBR1 (0.60) | ACVR1AURKATTKAURKBINCENP | |
| SCHEMBL35327 | 0.80 | TGFBR1 (0.60) | ACVR1AURKATTKAURKBINCENP | |
| SCHEMBL4017563 | 0.80 | PIK3CD (0.54) | ACVR1AURKATTKAURKBINCENP | |
| SCHEMBL30583075 | 0.79 | PIK3CA (0.59) | ACVR1AURKATTKAURKBINCENP | |
| SCHEMBL19991864 | 0.79 | PIK3CA (0.59) | ACVR1AURKATTKAURKBINCENP | |
| SCHEMBL22190051 | 0.78 | GRIA2 (0.54) | CAMKK1CAMKK2NPC1ESR1TP53 | |
| SCHEMBL22189993 | 0.78 | GRIA2 (0.54) | CAMKK1CAMKK2NPC1ESR1TP53 | |
| SCHEMBL22189991 | 0.78 | GRIA2 (0.54) | CAMKK1CAMKK2NPC1ESR1TP53 | |
| SCHEMBL12074333 | 0.77 | PIK3CA (0.65) | ACVR1AURKATTKAURKBINCENP | |
| SCHEMBL21982345 | 0.76 | ACVR1 (0.52) | ACVR1AURKATTKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |