Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907284 | 0.90 | KDM4E (0.49) | HPGDKDM4ECYP1A2ALDH1A1NPC1 | |
| SCHEMBL15028056 | 0.86 | NR1H4 (0.53) | HPGDKDM4ECYP1A2ALDH1A1NPC1 | |
| SCHEMBL2458629 | 0.84 | NR1H4 (0.51) | KDM4ECYP1A2GCKBRAFHDAC1 | |
| SCHEMBL29406430 | 0.83 | SLC6A4 (0.49) | HPGDKDM4ECYP1A2ALDH1A1SLC6A4 | |
| SCHEMBL1977659 | 0.83 | SLC6A4 (0.49) | HPGDKDM4ECYP1A2ALDH1A1SLC6A4 | |
| SCHEMBL21274571 | 0.83 | HPGD (0.52) | HPGDKDM4ECYP1A2ALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL2454106 | 0.82 | BRAF (0.57) | HPGDKDM4ECYP1A2ALDH1A1SLC6A4 | |
| SCHEMBL3139349 | 0.80 | HPGD (0.47) | HPGDKDM4ECYP1A2ALDH1A1SLC6A4 | |
| SCHEMBL146258 | 0.80 | KDM4E (0.62) | HPGDKDM4ECYP1A2ALDH1A1NPC1 | |
| SCHEMBL29502160 | 0.80 | KDM4E (0.62) | HPGDKDM4ECYP1A2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117254-A1 | PIPERIDINE AMIDES AS MODULATORS OF THE GHRELIN RECEPTOR | PROSIDION LIMITED (GB) | 2011-09-29 | — | — | WO | disclosed |