Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 9/20 | 0.50 |
| ▸ | APEH | P13798 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843692 | 0.86 | PPME1 (0.41) | PPME1APEHHTR6HDAC3HDAC4 | |
| SCHEMBL3843696 | 0.86 | PPME1 (0.41) | PPME1APEHHTR6HDAC3HDAC4 | |
| SCHEMBL299897 | 0.85 | HDAC6 (0.44) | PPME1APEHHDAC3HDAC1HDAC2 | |
| SCHEMBL299898 | 0.85 | HDAC6 (0.44) | PPME1APEHHDAC3HDAC1HDAC2 | |
| SCHEMBL14874714 | 0.76 | MMP8 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14874713 | 0.76 | MMP8 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18572538 | 0.74 | HDAC3 (0.45) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL295895 | 0.71 | HDAC1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL295896 | 0.71 | HDAC1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20849780 | 0.70 | PTGDR2 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063115-A1 | BICYCLIC COMPOUNDS AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2022-03-31 | — | — | WO | disclosed |