Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.52 |
| ▸ | FNTB | P49356 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24304134 | 0.79 | TP53 (0.63) | FNTAFNTBTP53MAPTMEN1 | |
| SCHEMBL1955351 | 0.74 | RECQL (0.54) | MAPTKMT2ARECQLALDH1A1LMNA | |
| SCHEMBL1955354 | 0.74 | RECQL (0.54) | MAPTKMT2ARECQLALDH1A1LMNA | |
| SCHEMBL21354384 | 0.71 | NR4A2 (0.40) | MAPTMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL21354382 | 0.71 | NR4A2 (0.40) | MAPTMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9748440 | 0.71 | HTR3A (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3546699 | 0.68 | NPC1 (0.49) | TP53MAPTMEN1KMT2ARECQL | |
| SCHEMBL3546695 | 0.68 | NPC1 (0.49) | TP53MAPTMEN1KMT2ARECQL | |
| SCHEMBL8173738 | 0.67 | GABRA1 (0.56) | MAPTMEN1KMT2AUSP2RECQL | |
| SCHEMBL25337533 | 0.67 | MAPT (0.45) | MAPTMEN1KMT2ARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079246-A1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2022-04-21 | — | — | WO | disclosed |
| EP-3984535-A1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | Albert-Ludwigs-Universität Freiburg (DE) | 2022-04-20 | — | — | EP | disclosed |