Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | APAF1 | O14727 | 3/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212590 | 0.82 | MAPT (0.63) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL12352057 | 0.76 | MAPT (0.76) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL18791129 | 0.73 | MAOA (0.67) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL15700128 | 0.73 | ALDH1A1 (0.60) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL30589283 | 0.72 | RAB9A (0.54) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL18398708 | 0.72 | RAB9A (0.54) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL21939350 | 0.71 | MAPT (0.53) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL881115 | 0.71 | MAPT (0.77) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL10696564 | 0.70 | NSD2 (0.56) | MAPTLMNAALDH1A1MAPK1HTT | |
| SCHEMBL7913503 | 0.70 | MAPT (0.61) | MAPTKDM4ELMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324954-B1 | AMINONAPTHOQUINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR BLOCKING UBIQUITINATION-PROTEASOME SYSTEM IN DISEASES | CALGENT BIOTECHNOLOGY CO LTD (TW) | 2022-03-09 | — | — | EP | disclosed |