Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14221228 | 0.81 | HDAC1 (0.70) | TSHRRECQLSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9326104 | 0.81 | TSHR (0.57) | TSHRRECQLHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22192209 | 0.81 | RAB9A (0.55) | TSHRSMN1; SMN2ALDH1A1CYP1A2RAB9A | |
| SCHEMBL10387988 | 0.81 | ALDH1A1 (0.64) | TSHRRECQLSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10475269 | 0.80 | RECQL (0.71) | TSHRRECQLHTTSMN1; SMN2HPGD | |
| SCHEMBL10474315 | 0.79 | ITGB3 (0.54) | TSHRRECQLHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17308837 | 0.79 | KDM4E (0.58) | TSHRRECQLHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11962158 | 0.78 | PLK1 (1.00) | PLK1TSHRHTTSMN1; SMN2HPGD | |
| SCHEMBL12839873 | 0.78 | PLK1 (0.87) | PLK1TSHRHTTSMN1; SMN2HPGD | |
| SCHEMBL2555132 | 0.78 | ALDH1A1 (0.59) | TSHRRECQLSMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022052014-A1 | CLASS OF PLATINUM COMPOUNDS FOR TREATING CANCER, AND METHOD FOR PREPARATION THEREOF | 上海海聚生物科技有限公司 | 2022-03-17 | — | — | WO | disclosed |