Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159298 | 0.76 | HTT (0.34) | HTT | |
| SCHEMBL21159294 | 0.72 | HTT (0.36) | HTT | |
| SCHEMBL9323882 | 0.69 | AHCY (0.34) | HTTAHCY | |
| SCHEMBL21159370 | 0.69 | JAK3 (0.40) | HTT | |
| SCHEMBL11159094 | 0.65 | IRAK4 (0.47) | — | |
| SCHEMBL1800304 | 0.65 | IRAK4 (0.47) | — | |
| SCHEMBL9323869 | 0.65 | RAB9A (0.38) | HTT | |
| SCHEMBL22787550 | 0.62 | NAE1 (0.42) | — | |
| SCHEMBL22787540 | 0.62 | NAE1 (0.42) | — | |
| SCHEMBL22787468 | 0.62 | NAE1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985007-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-04-20 | — | — | EP | disclosed |