Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 7/20 | 0.33 |
| ▸ | JAK3 | P52333 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159370 | 0.84 | JAK3 (0.40) | HTTJAK1JAK3JAK2KMT2A | |
| SCHEMBL21159570 | 0.84 | JAK2 (0.37) | HTTJAK1JAK3JAK2KMT2A | |
| SCHEMBL21159298 | 0.77 | HTT (0.34) | HTTJAK1JAK3 | |
| SCHEMBL24286016 | 0.72 | HTT (0.31) | HTT | |
| SCHEMBL21159371 | 0.72 | HTR1A (0.39) | HTTMAPTKMT2A | |
| SCHEMBL21159593 | 0.72 | LMNA (0.34) | JAK1JAK3JAK2WDR5KMT2A | |
| SCHEMBL21159571 | 0.69 | JAK3 (0.46) | HTTJAK1JAK3JAK2KMT2A | |
| SCHEMBL21159272 | 0.68 | JAK3 (0.42) | JAK1JAK3JAK2KMT2AMAP4K4 | |
| SCHEMBL9323882 | 0.67 | AHCY (0.34) | HTTJAK3 | |
| SCHEMBL8856262 | 0.65 | HTT (0.42) | HTTGAAMAPTRXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |