Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 19/20 | 0.75 |
| ▸ | UBA3 | Q8TBC4 | 19/20 | 0.75 |
| ▸ | UBA1 | P22314 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22787485 | 0.86 | NAE1 (1.00) | NAE1UBA3UBA1 | |
| SCHEMBL22787484 | 0.79 | NAE1 (0.49) | NAE1UBA3 | |
| SCHEMBL22787521 | 0.78 | NAE1 (0.86) | NAE1UBA3UBA1 | |
| SCHEMBL22787574 | 0.75 | NAE1 (0.75) | NAE1UBA3 | |
| SCHEMBL24286006 | 0.75 | NAE1 (0.75) | NAE1UBA3 | |
| SCHEMBL24286412 | 0.74 | P2RY12 (0.52) | NAE1UBA3 | |
| SCHEMBL22787463 | 0.73 | NAE1 (0.75) | NAE1UBA3 | |
| SCHEMBL22787515 | 0.73 | NAE1 (0.75) | NAE1UBA3 | |
| SCHEMBL22787469 | 0.72 | AHCY (0.48) | NAE1UBA3UBA1 | |
| SCHEMBL22787487 | 0.72 | AURKA (0.47) | NAE1UBA3AURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985007-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-04-20 | — | — | EP | disclosed |