Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.45 |
| ▸ | CPT2 | P23786 | 2/20 | 0.43 |
| ▸ | CPT1A | P50416 | 2/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286598 | 0.89 | RORC (0.49) | RORCNR1I2CPT2CPT1ACPT1B | |
| SCHEMBL24286490 | 0.86 | RORC (0.49) | RORCNR1I2CPT2CPT1ACPT1B | |
| SCHEMBL24286684 | 0.86 | RORC (0.55) | RORCNR1I2RORARORB | |
| SCHEMBL24286447 | 0.84 | CPT1A (0.51) | RORCNR1I2CPT2CPT1ACPT1B | |
| SCHEMBL24286712 | 0.84 | RORC (0.50) | RORCNR1I2CPT2CPT1ACPT1B | |
| SCHEMBL18312294 | 0.83 | RORC (0.64) | RORCNR1I2 | |
| SCHEMBL24286363 | 0.82 | RORC (0.49) | RORCNR1I2CPT2CPT1ACPT1B | |
| SCHEMBL24840211 | 0.82 | RORC (0.59) | RORCNR1I2RORARORBHTR6 | |
| SCHEMBL24286298 | 0.80 | ALDH1A1 (0.49) | RORC | |
| SCHEMBL24840258 | 0.80 | RORC (0.57) | RORCNR1I2CPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307738-B1 | ARYL DIHYDRO-2H-BENZO[B][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE | UNIV MICHIGAN REGENTS (US) | 2022-04-20 | — | — | EP | disclosed |