Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.62 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429904 | 0.90 | MGLL (0.75) | MGLLGPR119ABHD6LIPEFFAR4 | |
| SCHEMBL2431744 | 0.89 | MGLL (0.52) | MGLLGPR119USP30NR1H2RXRA | |
| SCHEMBL2426895 | 0.88 | MGLL (0.62) | MGLLFFAR4 | |
| SCHEMBL2420452 | 0.84 | MGLL (0.58) | MGLL | |
| SCHEMBL2427031 | 0.83 | MGLL (0.57) | MGLL | |
| SCHEMBL2423590 | 0.81 | MGLL (0.55) | MGLLGPR119 | |
| SCHEMBL2427027 | 0.81 | MGLL (0.55) | MGLLGPR119 | |
| SCHEMBL2424183 | 0.81 | MGLL (0.55) | MGLLGPR119 | |
| SCHEMBL2424131 | 0.81 | MGLL (0.48) | MGLLGPR119ABHD6USP30LIPE | |
| SCHEMBL2424111 | 0.81 | MGLL (0.59) | MGLLGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | PFIZER INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | FAAH, FAAH2, FFAR1 | MGLL 246/4885GPR119 58/4885ABHD6 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.