Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24287510 | 0.71 | ALDH1A1 (0.39) | ALDH1A1KMT2ANPSR1LMNAMEN1 | |
| SCHEMBL24287774 | 0.68 | P2RY1 (0.40) | MAPT | |
| SCHEMBL11038905 | 0.66 | MAPT (0.62) | MAPTALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL382385 | 0.66 | MAPT (0.62) | MAPTALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL29450004 | 0.66 | MAPT (0.62) | MAPTALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL27449327 | 0.66 | GAA (0.42) | MAPTALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL27710618 | 0.66 | KMT2A (0.39) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL14218340 | 0.66 | RAD52 (0.56) | MAPTALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL5549485 | 0.65 | ALDH1A1 (0.39) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL14050665 | 0.65 | MAPT (0.45) | MAPTALDH1A1GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076629-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |