Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 19/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24287510 | 0.84 | ALDH1A1 (0.39) | TP53 | |
| SCHEMBL24287535 | 0.75 | P2RY1 (0.40) | P2RY1TP53MAPT | |
| SCHEMBL24287256 | 0.74 | L3MBTL1 (0.45) | P2RY1TP53MAPT | |
| SCHEMBL29516261 | 0.73 | KDM4E (0.60) | P2RY1MAPT | |
| SCHEMBL24287534 | 0.73 | KDM4E (0.60) | P2RY1MAPT | |
| SCHEMBL24287526 | 0.68 | MAPT (0.39) | MAPT | |
| SCHEMBL26813109 | 0.68 | MAPT (0.40) | P2RY1TP53MAPT | |
| SCHEMBL127278 | 0.65 | ALDH1A1 (0.48) | P2RY1TP53MAPT | |
| SCHEMBL30500977 | 0.65 | ALDH1A1 (0.48) | P2RY1TP53MAPT | |
| SCHEMBL13818364 | 0.63 | P2RY1 (0.57) | P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076629-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |