Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 12/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27095285 | 0.74 | MAPK8 (0.40) | MAPK8ALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL30838098 | 0.74 | MAPK8 (0.40) | MAPK8ALDH1A1DPP4 | |
| SCHEMBL30838096 | 0.73 | CDK2 (0.40) | MAPK8DPP4 | |
| SCHEMBL24288096 | 0.73 | RPS6KA3 (0.44) | MAPK8DPP4 | |
| SCHEMBL24288064 | 0.73 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL24288152 | 0.72 | RPS6KA3 (0.47) | MAPK8 | |
| Hydrochloric Acid SCHEMBL30837986 | 0.72 | CHRM3 (0.47) | ACKR3 | |
| SCHEMBL30837994 | 0.72 | MAPK8 (0.39) | MAPK8DPP4 | |
| Hydrochloric Acid SCHEMBL30838027 | 0.71 | MAPK8 (0.39) | MAPK8DPP4 | |
| SCHEMBL24288090 | 0.71 | HRH4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |