Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.38 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.38 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.38 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | EPHB1 | P54762 | 1/20 | 0.38 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.38 |
| ▸ | SIK1 | P57059 | 1/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.38 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288255 | 0.84 | USP2 (0.42) | FEN1MAPK14EPHA2MAPK8ALOX5AP | |
| SCHEMBL24288152 | 0.84 | RPS6KA3 (0.47) | RPS6KA3FEN1MAPK14ABL1MAPK8 | |
| SCHEMBL24288094 | 0.83 | CYP11B2 (0.41) | RPS6KA3FEN1MAPK14SIK1SIK2 | |
| SCHEMBL24288140 | 0.81 | KMO (0.38) | FEN1MAPK14ALOX5APDPP4KMO | |
| SCHEMBL27095191 | 0.78 | KMO (0.36) | FEN1ABL1ALOX5APDPP4KMO | |
| SCHEMBL24288091 | 0.77 | MAP4K4 (0.40) | MAPK14ABL1EPHA2MAPK8DPP4 | |
| Hydrochloric Acid SCHEMBL30838107 | 0.76 | MAP4K4 (0.40) | MAPK14ABL1EPHA2MAPK8DPP4 | |
| SCHEMBL30837994 | 0.76 | MAPK8 (0.39) | RPS6KA3MAPK14MAPK8GAKDPP4 | |
| Hydrochloric Acid SCHEMBL30838027 | 0.75 | MAPK8 (0.39) | RPS6KA3MAPK14MAPK8GAKDPP4 | |
| SCHEMBL27095285 | 0.74 | MAPK8 (0.40) | RPS6KA3MAPK14MAPK8GAKDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |