Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 5/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 4/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30838107 | 0.99 | MAP4K4 (0.40) | MAP4K4MAPK9CSNK1DPRKD2CSNK1A1 | |
| SCHEMBL24288255 | 0.79 | USP2 (0.42) | MAP4K4MAPK9CSNK1DPRKD2CSNK1A1 | |
| SCHEMBL24288096 | 0.77 | RPS6KA3 (0.44) | MAPK9MAPK8DPP4MAPK14MAP4K5 | |
| SCHEMBL24288109 | 0.75 | MAP4K4 (0.36) | MAP4K4MAPK9CSNK1DPRKD2CSNK1A1 | |
| SCHEMBL24288152 | 0.74 | RPS6KA3 (0.47) | MAPK8MAPK14ABL1 | |
| SCHEMBL24288112 | 0.73 | MAP4K4 (0.35) | MAP4K4MAPK9CSNK1DPRKD2CSNK1A1 | |
| SCHEMBL24288090 | 0.72 | HRH4 (0.45) | ABL1HRH4 | |
| Hydrochloric Acid SCHEMBL30838015 | 0.72 | HRH4 (0.45) | ABL1HRH4 | |
| SCHEMBL30837994 | 0.71 | MAPK8 (0.39) | MAP4K4MAPK9CSNK1DPRKD2PRKD3 | |
| Hydrochloric Acid SCHEMBL30838027 | 0.70 | MAPK8 (0.39) | MAP4K4MAPK9CSNK1DPRKD2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |