Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 8/20 | 0.39 |
| ▸ | CASP7 | P55210 | 8/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288096 | 0.84 | RPS6KA3 (0.44) | MAPK9MAPK14MAP4K5NPC1RAB9A | |
| SCHEMBL24288152 | 0.81 | RPS6KA3 (0.47) | BCL6CYP2D6MAPK14MAPK8ALOX5AP | |
| SCHEMBL24288091 | 0.79 | MAP4K4 (0.40) | CLK4LMNAMAPK1MAP4K4MAPK9 | |
| Hydrochloric Acid SCHEMBL30838107 | 0.78 | MAP4K4 (0.40) | CLK4LMNAMAPK1MAP4K4MAPK9 | |
| SCHEMBL24288140 | 0.77 | KMO (0.38) | MAPK14DPP4ALOX5APFEN1 | |
| SCHEMBL24288064 | 0.77 | ALDH1A1 (0.47) | USP2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL24288090 | 0.77 | HRH4 (0.45) | METMERTK | |
| Hydrochloric Acid SCHEMBL30838015 | 0.76 | HRH4 (0.45) | METMERTK | |
| Hydrochloric Acid SCHEMBL30838088 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MEN1KMT2ACYP3A4 | |
| SCHEMBL24288109 | 0.75 | MAP4K4 (0.36) | ALDH1A1CLK4MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |