SCHEMBL242884

SCHEMBL242884

C=CCC1OC(=O)C(CC=C)OC1=O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.41
CTRC Q99895 2/20 0.41
F2 P00734 1/20 0.41
ALDH1A1 P00352 1/20 0.37
SLC2A1 P11166 1/20 0.37
ELANE P08246 1/20 0.30
CTSG P08311 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15826171 0.87 PRSS1 (0.39) PRSS1CTRCF2ALDH1A1SLC2A1
SCHEMBL3185827 0.83 PRSS1 (0.38) PRSS1CTRCF2ALDH1A1SLC2A1
SCHEMBL3975877 0.77 PRSS1 (0.38) PRSS1CTRCF2SLC2A1
SCHEMBL1364944 0.75 FAAH (0.34) PRSS1CTRCF2
SCHEMBL8243272 0.73
SCHEMBL6884389 0.72
SCHEMBL3977462 0.72 FAAH (0.38) PRSS1CTRCF2ALDH1A1
SCHEMBL12532875 0.71 ALDH1A1 (0.36) PRSS1CTRCF2ALDH1A1SLC2A1
SCHEMBL12532888 0.71 ALDH1A1 (0.36) PRSS1CTRCF2ALDH1A1SLC2A1
SCHEMBL12532882 0.71 ALDH1A1 (0.36) PRSS1CTRCF2ALDH1A1SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385002-B2 Process for making esters of 2-acetoxyalkanoic acids using a 3,6-dialkyl-1,4-dioxane-2,5-dione or poly-(alpha-hydroxyalkanoic acid) as a starting material NATUREWORKS LLC (US) 2019-08-20 US claimed
US-20180208537-A1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL NATUREWORKS LLC (US) 2018-07-26 US claimed
EP-3110787-B1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL NATUREWORKS LLC (US) 2018-04-11 EP claimed
US-20170066708-A1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL NATUREWORKS, LLC 2017-03-09 US claimed
EP-3110787-A1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL NatureWorks LLC (US) 2017-01-04 EP claimed
EP-2516413-B1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME EVONIK CORP (US) 2016-04-13 EP claimed
WO-2015127374-A1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL NATUREWORKS LLC (US) 2015-08-27 WO claimed
US-8399686-B2 Process for preparing cyclic esters comprising unsaturated functional groups and polyesters prepared from same EVONIK DEGUSSA CORPORATION (US) 2013-03-19 US claimed
US-8323678-B2 Implantable medical devices comprising poly[l-lactide-co-(3,6-dialkyl-1,4-dioxane-2,5-dione)] ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-12-04 US claimed
EP-2516413-A1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME Evonik Degussa Corporation (US) 2012-10-31 EP claimed
US-20120004324-A1 Process for Preparing Cyclic Esters Comprising Unsaturated Functional Groups and Polyesters Prepared From Same EVONIK OPERATIONS GMBH (DE) 2012-01-05 US claimed
US-20110270387-A1 Implantable Medical Devices Comprising Poly[L-Lactide-Co-(3,6-Dialkyl-1,4-Dioxane-2,5-Dione)] ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2011-11-03 US claimed
WO-2011084466-A1 PROCESS FOR PREPARING CYCLIC ESTERS COMPRISING UNSATURATED FUNCTIONAL GROUPS AND POLYESTERS PREPARED FROM SAME SURMODICS PHARMACEUTICALS, INC. (US) 2011-07-14 WO claimed
US-20210277275-A1 CROSSLINKED COATINGS STEVENS DAVID M (US) 2021-09-09 US disclosed
EP-3333148-B1 PROCESS FOR MAKING A 2-ACETOXYALKANOIC ESTER NATUREWORKS LLC (US) 2020-10-14 EP disclosed
US-10414714-B2 Process for making esters of 2-acetoxyalkanoic acids using a 3,6-dialkyl-1,4-dioxane-2,5-dione or poly-(alpha-hydroxyalkanoic acid) as a starting material NATUREWORKS LLC (US) 2019-09-17 US disclosed
US-20060194071-A1 Developer carrying member and development apparatus CANON KABUSHIKI KAISHA (JP) 2006-08-31 US disclosed
US-20050287484-A1 Resin-coated carrier for electrophotographic developer CANON KABUSHIKI KAISHA (JP) 2005-12-29 US disclosed
WO-2005121207-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121206-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP AND SULFONIC ACID GROUP, AND PRODUCTION METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170066708-A1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL HACL2, ADH1A, HAAO PRSS1 2603/4885CTRC 1432/4885F2 1505/4885
US-20120004324-A1 Process for Preparing Cyclic Esters Comprising Unsaturated Functional Groups and Polyesters Prepared From Same PHOSPHO1, CETP, SGMS1 PRSS1 2848/4885CTRC 1282/4885F2 695/4885
US-10385002-B2 Process for making esters of 2-acetoxyalkanoic acids using a 3,6-dialkyl-1,4-dioxane-2,5-dione or poly-(alpha-hydroxyalkanoic acid) as a starting material HACL2, ADH1A, HAAO PRSS1 2603/4885CTRC 1432/4885F2 1505/4885
US-10414714-B2 Process for making esters of 2-acetoxyalkanoic acids using a 3,6-dialkyl-1,4-dioxane-2,5-dione or poly-(alpha-hydroxyalkanoic acid) as a starting material HACL2, ADH1A, HAAO PRSS1 2603/4885CTRC 1432/4885F2 1505/4885
US-20180208537-A1 PROCESS FOR MAKING ESTERS OF 2-ACETOXYALKANOIC ACIDS USING A 3,6-DIALKYL-1,4-DIOXANE-2,5-DIONE OR POLY-(ALPHA-HYDROXYALKANOIC ACID) AS A STARTING MATERIAL HACL2, ADH1A, HAAO PRSS1 2603/4885CTRC 1432/4885F2 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.