Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.38 |
| ▸ | TTR | P02766 | 4/20 | 0.38 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288760 | 0.90 | SLC22A12 (0.34) | SLC22A12TTREYA3CYP2C9ESR1 | |
| SCHEMBL21836672 | 0.81 | SLC6A2 (0.39) | SLC22A12EYA3ESR1HPGDMEN1 | |
| SCHEMBL24173026 | 0.75 | PRMT1 (0.33) | — | |
| SCHEMBL21836669 | 0.73 | MAPK1 (0.39) | SLC22A12TTREYA3CYP2C9ESR1 | |
| SCHEMBL15528192 | 0.72 | KDM4E (0.35) | MEN1THRBMAPK1KMT2AMAPK14 | |
| SCHEMBL24173221 | 0.71 | PRMT1 (0.35) | — | |
| SCHEMBL6105067 | 0.70 | PRMT1 (0.39) | HPGDALDH1A1KMT2A | |
| SCHEMBL21836691 | 0.68 | MAPK1 (0.37) | ALDH1A1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL20181603 | 0.68 | SLC22A12 (0.46) | SLC22A12TTREYA3CYP2C9ESR1 | |
| SCHEMBL21836684 | 0.67 | MAPK1 (0.34) | SLC22A12HPGDALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484600-B | URAT1 inhibitors for promoting uric acid excretion | 江苏新元素医药科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| EP-3632904-B1 | URAT1 INHIBITORS FOR PROMOTING URIC ACID EXCRETION | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-04-20 | — | — | EP | disclosed |