Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288747 | 0.81 | SLC22A12 (0.38) | SLC6A3THRBMAPK14ALDH1A1KMT2A | |
| SCHEMBL24173026 | 0.78 | PRMT1 (0.33) | — | |
| SCHEMBL24288760 | 0.76 | SLC22A12 (0.34) | SLC6A3THRBMAPK14ALDH1A1GAA | |
| SCHEMBL24173221 | 0.74 | PRMT1 (0.35) | — | |
| SCHEMBL21836679 | 0.71 | MAPK1 (0.47) | SLC6A2SLC6A3KMT2AMAPTLMNA | |
| SCHEMBL31053394 | 0.68 | HCAR2 (0.35) | ALDH1A1GAAALOX15KMT2AHRH3 | |
| SCHEMBL31053388 | 0.67 | ALDH1A1 (0.42) | ALDH1A1GAAALOX15KMT2AMEN1 | |
| SCHEMBL20181600 | 0.66 | MIF (0.43) | ALDH1A1GAAALOX15KMT2AMEN1 | |
| SCHEMBL8877953 | 0.65 | RARB (0.44) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL24592873 | 0.64 | SLC22A12 (0.38) | ALDH1A1ESR1ESR2MAPTSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597725-B2 | URAT1 inhibitor for promoting uric acid excretion | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2023-03-07 | — | — | US | disclosed |
| CN-108484600-B | URAT1 inhibitors for promoting uric acid excretion | 江苏新元素医药科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| EP-3632904-B1 | URAT1 INHIBITORS FOR PROMOTING URIC ACID EXCRETION | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-04-20 | — | — | EP | disclosed |
| EP-3632904-B1 | URAT1 INHIBITORS FOR PROMOTING URIC ACID EXCRETION | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-04-20 | — | — | EP | disclosed |
| US-20200262832-A1 | URAT1 INHIBITOR FOR PROMOTING URIC ACID EXCRETION | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2020-08-20 | — | — | US | disclosed |
| EP-3632904-A1 | URAT1 INHIBITOR FOR PROMOTING URIC ACID EXCRETION | Jiangsu Atom Bioscience And Pharmaceutical Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11597725-B2 | URAT1 inhibitor for promoting uric acid excretion | SLC10A6, SLC10A1, SLC28A1 | SLC6A2 109/4885SLC6A3 168/4885THRB 1992/4885 |
| US-20200262832-A1 | URAT1 INHIBITOR FOR PROMOTING URIC ACID EXCRETION | SLC10A6, SLC10A1, SLC28A1 | SLC6A2 109/4885SLC6A3 168/4885THRB 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.