Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288747 | 0.90 | SLC22A12 (0.38) | SLC22A12ALDH1A1MAPK1EYA3HPGD | |
| SCHEMBL30061970 | 0.78 | MAPK1 (0.34) | SLC22A12ALDH1A1MAPK1HPGDPOLB | |
| SCHEMBL21836684 | 0.78 | MAPK1 (0.34) | SLC22A12ALDH1A1MAPK1HPGDPOLB | |
| SCHEMBL21836672 | 0.76 | SLC6A2 (0.39) | SLC22A12ALDH1A1EYA3HPGDMEN1 | |
| SCHEMBL24288761 | 0.73 | POLB (0.34) | SLC22A12ALDH1A1HPGDMEN1LMNA | |
| SCHEMBL24173026 | 0.70 | PRMT1 (0.33) | — | |
| SCHEMBL24288699 | 0.69 | SLC22A12 (0.31) | SLC22A12 | |
| SCHEMBL15528192 | 0.67 | KDM4E (0.35) | MAPK1MEN1THRBKMT2AMAPK14 | |
| Lingdolinurad SCHEMBL18629797 | 0.67 | ALDH1A1 (0.41) | SLC22A12ALDH1A1MAPK1EYA3HPGD | |
| Lingdolinurad SCHEMBL29673183 | 0.67 | ALDH1A1 (0.41) | SLC22A12ALDH1A1MAPK1EYA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632904-B1 | URAT1 INHIBITORS FOR PROMOTING URIC ACID EXCRETION | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-04-20 | — | — | EP | disclosed |