Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL30107704 | 0.97 | CYP2C19 (0.31) | CYP2C19ALDH1A1 | |
| SCHEMBL28968487 | 0.97 | — | — | |
| SCHEMBL28968537 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL21295181 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| Zinc Ion SCHEMBL28968544 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL6662738 | 0.94 | TSHR (0.35) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL8612559 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| Silver SCHEMBL21295179 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| Lithium Ion SCHEMBL28968511 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL28968493 | 0.94 | CYP2C19 (0.32) | CYP2C19USP2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785523-B | Composition and application of alpha/beta composite nucleating agent for regulating and controlling mechanical properties of polypropylene | 华东理工大学 | 2023-10-10 | — | — | CN | claimed |
| EP-3293212-B1 | POLYMER COMPOSITION FOR CONTAINER CLOSURES | THAI POLYETHYLENE CO LTD (TH) | 2023-02-22 | — | — | EP | claimed |
| CN-115697700-A | Oriented polyethylene film and articles comprising the same | 陶氏环球技术有限责任公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115232353-A | Low-odor scratch-resistant polypropylene composition, expanded beads, preparation method of expanded beads and polypropylene expanded bead forming body | 中国石油化工股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-114800985-A | Rotational molding cross-linked polyethylene hand die and composition and preparation method thereof | 安徽锐途新材料科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-109486426-B | White-fog-proof and blue-light-proof hot-melt optical adhesive and preparation method thereof | 广州市隆创新材料有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-103497405-A | Nucleated master batch for improving production speed of polyethylene bottle cap | NANJING KING TECH CHINA CO LTD | 2014-01-08 | — | — | CN | claimed |
| WO-2014000820-A1 | INSULATING COMPOSITION FOR ELECTRICAL POWER APPLICATIONS | ABB RESEARCH LTD (CH) | 2014-01-03 | — | — | WO | claimed |
| US-8026305-B2 | Articles formed from nucleated polyethylene | FINA TECHNOLOGY INC (US) | 2011-09-27 | — | — | US | claimed |
| US-12600846-B2 | Polymeric substrate including a barrier layer | INV POLYPROPYLENE, LLC (US) | 2026-04-14 | — | — | US | disclosed |
| US-12576620-B2 | Modification of polypropylene resins with nucleating agents to enhance mechanical and barrier properties of films | Superior Plastics Extrusion Co. Inc. (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4031370-B1 | STAND UP POUCH WITH RECYCLED POLYETHYLENE | NOVA CHEMICALS INTERNATIONAL SA (CH) | 2026-02-25 | — | — | EP | disclosed |
| US-12491705-B2 | Stand up pouch with recycled polyethylene | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2025-12-09 | — | — | US | disclosed |
| US-20250223409-A1 | Process of Preparing Masterbatch Compositions and Their Use | MILLIKEN & COMPANY | 2025-07-10 | — | — | US | disclosed |
| CN-103497405-A | Nucleated master batch for improving production speed of polyethylene bottle cap | NANJING KING TECH CHINA CO LTD | 2014-01-08 | — | — | CN | disclosed |
| WO-2014000820-A1 | INSULATING COMPOSITION FOR ELECTRICAL POWER APPLICATIONS | ABB RESEARCH LTD (CH) | 2014-01-03 | — | — | WO | disclosed |
| EP-2497453-A1 | PLASTIC FILM HAVING OXYGEN ABSORBING FUNCTION AND INFUSION BAG | Hosokawa Yoko Co., Ltd. (JP) | 2012-09-12 | — | — | EP | disclosed |
| EP-2492092-A1 | PLASTIC FILM AND INFUSION BAG | Hosokawa Yoko Co., Ltd. (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120215196-A1 | PLASTIC FILM HAVING OXYGEN ABSORBING FUNCTION AND INFUSION BAG | HOSOKAWA YOKO CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
| US-20120201984-A1 | PLASTIC FILM AND INFUSION BAG | HOSOKAWA YOKO CO., LTD. (JP) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576620-B2 | Modification of polypropylene resins with nucleating agents to enhance mechanical and barrier properties of films | NUP93, HNRNPH1, NXF1 | CYP2C19 3995/4885USP2 1581/4885ALDH1A1 3775/4885 |
| US-12600846-B2 | Polymeric substrate including a barrier layer | ROS1, P4HTM, AHR | CYP2C19 995/4885USP2 2114/4885ALDH1A1 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.