Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474252 | 0.83 | NCF1 (0.51) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| SCHEMBL30059176 | 0.79 | HRH3 (0.59) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| SCHEMBL546487 | 0.79 | HRH3 (0.59) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| SCHEMBL6202441 | 0.78 | MAPT (0.54) | SMN1; SMN2RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL4779922 | 0.78 | HRH3 (0.54) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| Ammonia Solution, Strong SCHEMBL548075 | 0.77 | HRH3 (0.58) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| SCHEMBL14320176 | 0.77 | HRH3 (0.50) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| SCHEMBL15677807 | 0.76 | HIF1A (0.64) | HRH3HTTSMN1; SMN2NOS1NOS3 | |
| SCHEMBL16054673 | 0.75 | HRH3 (0.54) | NCF1HRH3HTTSMN1; SMN2NOS1 | |
| SCHEMBL4974297 | 0.75 | HTT (0.55) | NCF1HRH3HTTSMN1; SMN2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |