SCHEMBL2429121

SCHEMBL2429121

O=P1(O)Oc2c(cc(C3CCCCC3)cc2C2CCCCC2)-c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.33
KMO O15229 1/20 0.33
PTGS2 P35354 1/20 0.32
PTPN5 P54829 2/20 0.31
PTPN2 P17706 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.30
PTPRC P08575 1/20 0.30
PTPRF P10586 1/20 0.30
PTPN1 P18031 1/20 0.30
CDC25B P30305 1/20 0.30
STING1 Q86WV6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431432 0.88 ACMSD (0.35) PDK2KMOHDAC4HDAC2HDAC8
SCHEMBL11659153 0.85 PTGS2 (0.33) PDK2KMOPTGS2PTGDR2
SCHEMBL2437805 0.85 PTGS2 (0.37) KMOPTGS2PTPN5PTPN2PTGDR2
SCHEMBL2427175 0.84 PTPN5 (0.33) PTGS2PTPN5PTPN2
SCHEMBL2431571 0.84 PDK2 (0.33) PDK2KMOPTPRCPTPRFPTPN1
SCHEMBL2433301 0.83 PTGDR2 (0.32) PTPN5PTPN2PTGDR2PTPN1
SCHEMBL2435254 0.82 ASAH1 (0.32) KMO
SCHEMBL2434315 0.80 PDK2 (0.39) PDK2KMOHDAC4HDAC2HDAC8
SCHEMBL2434911 0.74 ASAH1 (0.34) PDK2KMO
SCHEMBL2441544 0.72 PDK2 (0.41) PDK2KMOHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed