SCHEMBL2441544

SCHEMBL2441544

O=P1(O)Oc2ccccc2-c2ccc(C3CCCCC3)cc21

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.41
KMO O15229 1/20 0.37
ACMSD Q8TDX5 2/20 0.36
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
CNR1 P21554 1/20 0.33
STING1 Q86WV6 1/20 0.33
S1PR1 P21453 3/20 0.33
DPP4 P27487 1/20 0.33
PGAM1 P18669 1/20 0.33
S1PR5 Q9H228 1/20 0.32
EPHX2 P34913 1/20 0.32
DHODH Q02127 1/20 0.32
ASAH1 Q13510 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359265 0.99 PDK2 (0.41) PDK2KMOACMSDHDAC4HDAC2
SCHEMBL9359279 0.99 PDK2 (0.41) PDK2KMOACMSDHDAC4HDAC2
SCHEMBL2434315 0.87 PDK2 (0.39) PDK2KMOACMSDHDAC4HDAC2
SCHEMBL9359269 0.84 PDK2 (0.38) PDK2KMOACMSDHDAC4HDAC2
SCHEMBL2431432 0.78 ACMSD (0.35) PDK2KMOACMSDHDAC4HDAC2
SCHEMBL2434911 0.76 ASAH1 (0.34) PDK2KMOACMSDS1PR1S1PR5
SCHEMBL29519147 0.74 GPR84 (0.35) DPP4
SCHEMBL2436265 0.74 GPR84 (0.35) DPP4
SCHEMBL2404538 0.74 ELANE (0.40) PDK2
SCHEMBL2429121 0.72 PDK2 (0.33) PDK2KMOHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed