SCHEMBL2429424

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2433158	0.89	ALDH1A1 (0.39)	DYRK1AMAPK1MAPTMEN1GAA
	SCHEMBL2432159	0.87	NPC1 (0.37)	DYRK1AKDRAXLMAPTMEN1
	SCHEMBL2432114	0.87	NPC1 (0.37)	DYRK1AKDRAXLMAPTMEN1
	SCHEMBL1136382	0.86	MAOB (0.40)	DYRK1APRKAA1MAPTGAAALDH1A1
	SCHEMBL1136119	0.86	MAOB (0.40)	DYRK1AKDRAXLPRKAA1GAA
	SCHEMBL2429944	0.84	MGAM (0.35)	DYRK1AKDRAXLMEN1GAA
	SCHEMBL2438266	0.83	PDE3B (0.38)	DYRK1AKDRAXLMAPTGAA
	SCHEMBL2461065	0.83	KDM4E (0.40)	DYRK1APLK4FLT4KDRFLT3
	SCHEMBL2432282	0.82	NPC1 (0.37)	DYRK1AMEN1GAAKMT2AALDH1A1
	SCHEMBL2429582	0.82	IDO1 (0.36)	DYRK1AMAPK1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.