SCHEMBL2461065

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2462928	0.87	PDE5A (0.41)	DYRK1AHRH3
	SCHEMBL2429424	0.83	DYRK1A (0.39)	KDM4EALDH1A1MAPTHPGDSMN1; SMN2
	SCHEMBL2461306	0.82	IMPDH2 (0.40)	KDM4EALDH1A1MAPTSMN1; SMN2ADORA3
	SCHEMBL2590584	0.82	TUBB4A (0.39)	KDRGPR84
	SCHEMBL2433158	0.82	ALDH1A1 (0.39)	KDM4EALDH1A1MAPTSMN1; SMN2GAA
	SCHEMBL1135960	0.82	MAOB (0.41)	KDM4EALDH1A1GAAKDRDYRK1A
	SCHEMBL2432181	0.81	HPGD (0.43)	KDM4EALDH1A1MAPTHPGDADORA3
	SCHEMBL2432114	0.81	NPC1 (0.37)	KDM4EALDH1A1MAPTHPGDSMN1; SMN2
	SCHEMBL2432159	0.81	NPC1 (0.37)	KDM4EALDH1A1MAPTSMN1; SMN2GAA
	SCHEMBL2458247	0.80	ALDH1A1 (0.40)	KDM4EALDH1A1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.