Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965867 | 0.74 | DRD2 (0.46) | DRD2SLC18A3HTR1ADRD1DRD5 | |
| SCHEMBL18591774 | 0.70 | PRCP (0.42) | DRD2SLC18A3HTR1ADRD1DRD5 | |
| SCHEMBL23693482 | 0.68 | SIGMAR1 (0.51) | DRD2SLC18A3HRH3CYP3A4PRCP | |
| SCHEMBL24294649 | 0.66 | SIGMAR1 (0.45) | DRD2KCNH2HRH3CYP3A4 | |
| SCHEMBL23664608 | 0.65 | HRH3 (0.41) | DRD2SLC18A3KCNH2HRH3CYP3A4 | |
| SCHEMBL18611442 | 0.65 | KDM1A (0.36) | DRD2HTR1A | |
| SCHEMBL11932474 | 0.65 | DRD2 (0.68) | DRD2KCNH2HRH3CYP3A4CYP2C9 | |
| SCHEMBL24453204 | 0.65 | ACHE (0.40) | HRH3 | |
| SCHEMBL9967721 | 0.64 | PRCP (0.48) | DRD2SLC18A3CYP3A4PRCP | |
| SCHEMBL22537840 | 0.64 | DRD2 (0.51) | DRD2CYP3A4HTR1ADRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |