Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27877359 | 0.84 | KEAP1 (0.46) | KEAP1NFE2L2LMNAALDH1A1MEN1 | |
| SCHEMBL21051000 | 0.84 | KEAP1 (0.46) | KEAP1NFE2L2LMNAALDH1A1MEN1 | |
| SCHEMBL27710862 | 0.82 | KEAP1 (0.45) | KEAP1NFE2L2LMNAALDH1A1MEN1 | |
| SCHEMBL28570325 | 0.79 | KEAP1 (0.45) | KEAP1NFE2L2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7590641 | 0.76 | KEAP1 (0.40) | KEAP1NFE2L2LMNAMEN1MAPT | |
| SCHEMBL27692266 | 0.75 | KEAP1 (0.39) | KEAP1NFE2L2LMNAMEN1MAPT | |
| SCHEMBL14996216 | 0.75 | HRH2 (0.41) | LMNAALDH1A1MEN1MAPTHTT | |
| SCHEMBL20601188 | 0.74 | CYP2C19 (0.39) | LMNAALDH1A1MAPTHTTKMT2A | |
| SCHEMBL9185112 | 0.74 | KDM4A (0.52) | ALDH1A1MAPTNPSR1CYP3A4 | |
| SCHEMBL11242944 | 0.72 | KDM4C (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089638-A1 | DITHIOCARBAMATE STAPLED PEPTIDES AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089638-A1 | DITHIOCARBAMATE STAPLED PEPTIDES AND METHODS OF MAKING AND USE THEREOF | TP53, TP53BP1, DNASE1L3 | KEAP1 1963/4885NFE2L2 3925/4885LMNA 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.