Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.68 |
| ▸ | RELA | Q04206 | 5/20 | 0.68 |
| ▸ | USP2 | O75604 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280247 | 0.82 | ALOX15 (0.75) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21262770 | 0.82 | RAB9A (0.60) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10357589 | 0.81 | SMN1; SMN2 (1.00) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1407405 | 0.79 | HSD17B10 (0.63) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17962550 | 0.79 | HPGD (0.57) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17279997 | 0.78 | RAB9A (0.69) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9071981 | 0.77 | HSD17B10 (0.69) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10358110 | 0.76 | MAPT (1.00) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17279878 | 0.75 | ALOX15 (0.65) | HPGDALOX15MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL22978372 | 0.75 | TNIK (0.62) | HPGDALOX15MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059884-A1 | ALDH INHIBITORS TO PROMOTE IMMUNE CELL EXPANSION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-04-13 | — | — | WO | claimed |
| WO-2023059884-A1 | ALDH INHIBITORS TO PROMOTE IMMUNE CELL EXPANSION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-04-13 | — | — | WO | disclosed |
| WO-2022076621-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |