SCHEMBL17280247

SCHEMBL17280247

Cc1ccccc1-c1cc(-c2cc(-c3ccccc3C)[nH]n2)n[nH]1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 7/20 0.75
MAPT P10636 7/20 0.75
RAB9A P51151 7/20 0.75
HPGD P15428 6/20 0.75
SMN1; SMN2 Q16637 5/20 0.75
NFKB1 P19838 4/20 0.75
NFKB2 Q00653 4/20 0.75
RELA Q04206 4/20 0.75
USP2 O75604 3/20 0.75
TSHR P16473 1/20 0.75
MEN1 O00255 8/20 0.69
KMT2A Q03164 8/20 0.69
NPC1 O15118 7/20 0.69
TP53 P04637 3/20 0.69
NPSR1 Q6W5P4 2/20 0.69
LMNA P02545 2/20 0.69
GLA P06280 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
ADORA3 P0DMS8 2/20 0.50
ALDH1A1 P00352 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17279997 0.91 RAB9A (0.69) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL17279878 0.88 ALOX15 (0.65) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL10357589 0.86 SMN1; SMN2 (1.00) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL10357782 0.86 MAPT (0.68) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL17943420 0.85 KMT2A (0.78) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL21262770 0.84 RAB9A (0.60) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL17943297 0.83 MAPT (0.66) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL24299072 0.82 HPGD (0.68) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL17279979 0.82 ALOX15 (0.62) ALOX15MAPTRAB9AHPGDSMN1; SMN2
SCHEMBL12567874 0.82 RAB9A (0.65) ALOX15MAPTRAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS ALOX15 1176/4885MAPT 342/4885RAB9A 1803/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 ALOX15 1404/4885MAPT 523/4885RAB9A 2127/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 ALOX15 3195/4885MAPT 3472/4885RAB9A 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.