Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790717 | 1.00 | PIK3CA (0.40) | PIK3CAMTORPDE10ALMNAHTT | |
| SCHEMBL20037726 | 0.83 | MAP4K4 (0.39) | PIK3CAMTORPDE10AMAP4K4KMT2A | |
| SCHEMBL9195108 | 0.82 | PDE10A (0.44) | PIK3CAMTORPDE10ALMNAHTT | |
| SCHEMBL20255203 | 0.81 | PDE10A (0.40) | PDE10ALMNAHTTPDE2APDE1B | |
| SCHEMBL9198277 | 0.81 | LMNA (0.61) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL16880317 | 0.80 | JAK2 (0.38) | LMNAHTTNPC1RAB9AKLF5 | |
| SCHEMBL30349708 | 0.79 | LMNA (0.43) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL458210 | 0.78 | PDE10A (0.39) | PIK3CAMTORPDE10ALMNAHTT | |
| SCHEMBL9219556 | 0.78 | HRH3 (0.50) | PDE10ALMNAHTTPDE2APDE1B | |
| SCHEMBL12832968 | 0.78 | NPC1 (0.56) | LMNAHTTNPC1RAB9AKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048605-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATIONS | 南昌奥瑞药业有限公司 | 2022-03-10 | — | — | WO | disclosed |