Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20443214 | 0.84 | NPC1 (0.37) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL9195108 | 0.83 | PDE10A (0.44) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL22007467 | 0.80 | ACHE (0.36) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20255732 | 0.79 | CDK4 (0.40) | CDK4CDK6 | |
| SCHEMBL9219556 | 0.79 | HRH3 (0.50) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL24299592 | 0.78 | PIK3CA (0.40) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL20255203 | 0.78 | PDE10A (0.40) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL30790717 | 0.78 | PIK3CA (0.40) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL9198277 | 0.78 | LMNA (0.61) | PDE10ALMNAHTTMEN1KMT2A | |
| SCHEMBL20038254 | 0.78 | PDE10A (0.41) | PDE10ALMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| EP-0577217-A1 | Tetrazolyl-(phenoxy and phenoxyalkyl) piperidininylpyridazines as antiviral agents | STERLING WINTHROP INC. (US) | 1994-01-05 | — | — | EP | disclosed |
| US-5242924-A | Tetrazolyl-(phenoxy and phenoxyalkyl)-piperidinylpyridazines as antiviral agents | STERLING WINTHROP INC. (US) | 1993-09-07 | — | — | US | disclosed |