SCHEMBL24300007

SCHEMBL24300007

CC(C)(C)OC(=O)NCc1cccc(-c2cccc3ccccc23)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.56
CREBBP Q92793 1/20 0.56
KDM4A O75164 1/20 0.50
GLS O94925 3/20 0.47
NQO2 P16083 1/20 0.46
HDAC1 Q13547 1/20 0.46
CCKBR P32239 1/20 0.46
BRD9 Q9H8M2 1/20 0.45
BAZ2B Q9UIF8 1/20 0.45
BAZ2A Q9UIF9 1/20 0.45
GRM2 Q14416 1/20 0.45
CTSS P25774 2/20 0.45
CTSK P43235 2/20 0.45
CTSB P07858 1/20 0.45
ACACB O00763 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
ACACA Q13085 1/20 0.44
PDCD1 Q15116 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21438426 0.87 BRD4 (0.48) BRD4CREBBPKDM4AGLSHDAC1
SCHEMBL12305686 0.86 BRD4 (0.57) BRD4CREBBPKDM4AGLSHDAC1
SCHEMBL21455905 0.86 BRD4 (0.48) BRD4CREBBPKDM4AGLSNQO2
SCHEMBL18664426 0.84 HDAC1 (0.60) BRD4CREBBPKDM4AGLSHDAC1
SCHEMBL30504293 0.84 HDAC1 (0.56) BRD4CREBBPKDM4AGLSHDAC1
SCHEMBL23617124 0.84 BRD4 (0.52) BRD4CREBBPKDM4AGLSHDAC1
SCHEMBL24299792 0.83 NAMPT (0.48) BRD4CREBBPKDM4AGLSNQO2
SCHEMBL22382955 0.82 BRD4 (0.57) BRD4CREBBPKDM4AGLSHDAC1
SCHEMBL23425556 0.81 BRD4 (0.44) BRD4CREBBPKDM4AGLSNQO2
SCHEMBL16410240 0.81 BRD4 (0.53) BRD4CREBBPKDM4AGLSHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220123235-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123235-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OXSR1, C1R BRD4 1134/4885CREBBP 2293/4885KDM4A 3539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.