SCHEMBL24299792

SCHEMBL24299792

CC(C)(C)OC(=O)NCc1cccc(-c2nccc3ccccc23)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.48
BRD4 O60885 3/20 0.48
KDM4A O75164 1/20 0.46
GLS O94925 3/20 0.45
CREBBP Q92793 1/20 0.45
ACACB O00763 2/20 0.43
CYP1A2 P05177 2/20 0.43
ACACA Q13085 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2D6 P10635 1/20 0.43
NQO2 P16083 1/20 0.43
HDAC1 Q13547 1/20 0.42
GRM2 Q14416 1/20 0.42
CKS1B P61024 1/20 0.41
SKP1 P63208 1/20 0.41
SKP2 Q13309 1/20 0.41
CTSB P07858 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24300007 0.83 BRD4 (0.56) NAMPTBRD4KDM4AGLSCREBBP
SCHEMBL31755970 0.81 BRD4 (0.49) NAMPTBRD4KDM4AGLSCREBBP
SCHEMBL4402738 0.81 BRD4 (0.49) NAMPTBRD4KDM4AGLSCREBBP
SCHEMBL24299843 0.80 MAPK1 (0.38) CREBBP
SCHEMBL18664426 0.80 HDAC1 (0.60) BRD4KDM4AGLSCREBBPHDAC1
SCHEMBL30504293 0.80 HDAC1 (0.56) NAMPTBRD4KDM4AGLSCREBBP
SCHEMBL24000658 0.78 PARP1 (0.53) NAMPTBRD4GLSCREBBPCYP1A2
SCHEMBL24804174 0.78 JAK3 (0.53) BRD4CREBBP
SCHEMBL301717 0.78 PRMT6 (0.56) NAMPTBRD4GLSCREBBPCYP3A4
SCHEMBL21455344 0.77 CFD (0.47) NAMPTBRD4GLSCREBBPACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220123235-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123235-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OXSR1, C1R NAMPT 3827/4885BRD4 1134/4885KDM4A 3539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.