Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25398389 | 0.92 | FFAR4 (0.46) | FFAR4FFAR1L3MBTL1DNM1DGKA | |
| SCHEMBL31243816 | 0.89 | FFAR4 (0.46) | FFAR4FFAR1L3MBTL1DNM1DGKA | |
| SCHEMBL25398997 | 0.89 | FFAR4 (0.46) | FFAR4FFAR1L3MBTL1DNM1DGKA | |
| SCHEMBL27323822 | 0.89 | DGKA (0.51) | FFAR4FFAR1DNM1DGKAPAM | |
| SCHEMBL24011926 | 0.87 | L3MBTL1 (0.53) | FFAR4FFAR1L3MBTL1DNM1DGKA | |
| SCHEMBL26624052 | 0.87 | FFAR4 (0.67) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL22807260 | 0.87 | FFAR4 (0.67) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL25399220 | 0.87 | FFAR4 (0.67) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7854619 | 0.86 | FFAR4 (0.70) | FFAR4FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL27386146 | 0.85 | DNM1 (0.48) | FFAR4FFAR1L3MBTL1DNM1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118922409-A | Asymmetric piperazine-based cationic lipids | 翻译生物公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. | 2023-11-09 | — | — | US | disclosed |
| WO-2023178167-A1 | ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| CN-116457027-A | Piperazine-based cationic lipids | 翻译生物公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022066916-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2022-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | NPC1L1, SREBF2, NPC1 | FFAR4 1637/4885FFAR1 645/4885L3MBTL1 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.