Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428479 | 0.86 | NOX1 (0.37) | NOX1MAPTMAPK1GAANPC1 | |
| SCHEMBL2425936 | 0.82 | S100B (0.37) | S100BNOX1MAPTMAPK1GAA | |
| SCHEMBL972682 | 0.80 | SNCA (0.46) | S100BNOX1MAPTMAPK1GAA | |
| SCHEMBL2429634 | 0.80 | S100B (0.41) | S100BNOX1MAPTMAPK1GAA | |
| SCHEMBL14321240 | 0.78 | S100B (0.39) | S100BNOX1MAPTMAPK1GAA | |
| SCHEMBL2428865 | 0.78 | SNCA (0.42) | S100BNOX1MAPTMAPK1GAA | |
| Iodide SCHEMBL3711619 | 0.78 | NOX1 (0.55) | NOX1MAPTMAPK1GAANPC1 | |
| Iodide SCHEMBL3711622 | 0.78 | NOX1 (0.55) | NOX1MAPTMAPK1GAANPC1 | |
| Iodide SCHEMBL3711621 | 0.78 | NOX1 (0.55) | NOX1MAPTMAPK1GAANPC1 | |
| SCHEMBL2428034 | 0.77 | S100B (0.38) | S100BNOX1MAPTMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547668-A1 | TOLUIDINE BLUE DERIVATIVES AS PHOTOSENSITISING COMPOUNDS | Pharmalucia Ltd (GB) | 2013-01-23 | — | — | EP | disclosed |
| US-20120328530-A1 | TOLUIDINE BLUE DERIVATIVES AS PHOTOSENSITISING COMPOUNDS | PHARMALUCIA LIMITED (GB) | 2012-12-27 | — | — | US | disclosed |
| WO-2011114137-A1 | TOLUIDINE BLUE DERIVATIVES AS PHOTOSENSITISING COMPOUNDS | PHARMALUCIA LIMITED (GB) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328530-A1 | TOLUIDINE BLUE DERIVATIVES AS PHOTOSENSITISING COMPOUNDS | TYR, TST, TH | S100B 1790/4885NOX1 635/4885MAPT 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.