Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20667980 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20667990 | 0.71 | KDM4E (0.72) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20667975 | 0.67 | HTT (0.69) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20668099 | 0.65 | GAA (0.68) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20667991 | 0.62 | LMNA (0.86) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20667994 | 0.59 | KDM4E (0.75) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20659861 | 0.58 | MAPT (0.65) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20667920 | 0.58 | MAPT (0.62) | ALDH1A1KDM4EMAPK1LMNAHTT | |
| SCHEMBL20667974 | 0.57 | KDM4E (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL28561887 | 0.56 | LIPG (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220117968-A1 | THIENO[2,3-D)PYRIMIDINES AND BENZOFURO(3,2-D)PYRIMIDINES AS ANTIMICROBIAL AGENTS | SAINT LOUIS UNIVERSITY | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220117968-A1 | THIENO[2,3-D)PYRIMIDINES AND BENZOFURO(3,2-D)PYRIMIDINES AS ANTIMICROBIAL AGENTS | TYMS, DPYD, UMPS | ALDH1A1 924/4885KDM4E 2186/4885MAPK1 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.