SCHEMBL2430718

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15177306	0.84	APP (0.73)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL2430633	0.82	APP (0.59)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL2427073	0.81	RAB9A (0.63)	NPC1RAB9AALDH1A1KDM4EKMT2A
	SCHEMBL24320031	0.80	NPC1 (0.74)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL1726415	0.78	APP (0.66)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL1985593	0.78	APP (0.66)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL217156	0.78	RAB9A (0.75)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL26603206	0.78	APP (0.69)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL2904371	0.78	APP (0.66)	APPNPC1RAB9AALDH1A1PAX8
	SCHEMBL2429114	0.78	APP (0.58)	APPNPC1RAB9AALDH1A1PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.