SCHEMBL1726415

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bromide SCHEMBL1726261	0.98	NPC1 (0.65)	APPNPC1RAB9AKDM4EGFER
	SCHEMBL15177306	0.90	APP (0.73)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL2257095	0.86	APP (0.73)	APPNPC1RAB9AKDM4EGFER
	SCHEMBL24320031	0.85	NPC1 (0.74)	APPNPC1RAB9AKDM4EGFER
	SCHEMBL217156	0.83	RAB9A (0.75)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL26603206	0.83	APP (0.69)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL2904371	0.83	APP (0.66)	APPNPC1RAB9AKDM4EGFER
	SCHEMBL1985593	0.83	APP (0.66)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL6491308	0.83	ALDH1A3 (0.69)	APPNPC1RAB9AKDM4EALDH1A1
	SCHEMBL1727974	0.81	APP (0.52)	APPNPC1RAB9AKDM4EGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.