Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155975 | 0.87 | AOC3 (0.50) | KMT2ALMNAMEN1CYP3A4HPGD | |
| SCHEMBL13510571 | 0.87 | AOC3 (0.50) | KMT2ALMNAMEN1CYP3A4HPGD | |
| SCHEMBL13510574 | 0.87 | AOC3 (0.50) | KMT2ALMNAMEN1CYP3A4HPGD | |
| SCHEMBL24307460 | 0.85 | ALDH1A1 (0.43) | KMT2ALMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL24307696 | 0.84 | FABP3 (0.41) | KMT2ALMNAMEN1GABRA1GABRB2 | |
| SCHEMBL24307627 | 0.80 | KDM1A (0.43) | KMT2ALMNAMEN1GABRA1GABRB2 | |
| SCHEMBL13284155 | 0.78 | ALDH1A1 (0.45) | KMT2ALMNAMEN1TSHRSMN1; SMN2 | |
| SCHEMBL10037121 | 0.78 | GABRA1 (0.48) | KMT2ALMNAMEN1GABRA1GABRB2 | |
| SCHEMBL24307496 | 0.77 | MEN1 (0.42) | KMT2AMEN1 | |
| SCHEMBL17636908 | 0.74 | GABRA1 (0.50) | KMT2ALMNAMEN1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078306-A1 | LARGE STERIC HINDERANCE PALLADIUM-NITROGEN-HETEROCYCLIC CARBENE COMPLEX, PREPARATION METHOD FOR SAME, APPLICATIONS OF SAME, AND SYNTHESIS METHOD FOR SONIDEGIB BASED ON SAME | 中山大学 | 2022-04-21 | — | — | WO | disclosed |