Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420978 | 0.85 | LMNA (0.40) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL19505932 | 0.81 | GABRA1 (0.50) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL17636908 | 0.81 | GABRA1 (0.50) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL15494164 | 0.79 | SMN1; SMN2 (0.46) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL6579678 | 0.79 | GABRA1 (0.43) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| Hydrochloric Acid SCHEMBL29113135 | 0.79 | GABRA1 (0.43) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL812723 | 0.79 | GABRA1 (0.52) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL24592602 | 0.78 | GABRA1 (0.46) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL22429269 | 0.78 | SOAT1 (0.46) | GABRA1LMNAGABRG2GABRB3GABRB2 | |
| SCHEMBL24307685 | 0.78 | KMT2A (0.49) | GABRA1LMNAGABRG2GABRB3GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978346-A | Arylamine silane compound, propylene polymerization catalyst, preparation and application thereof | 中国石油天然气股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| US-10256419-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-04-09 | — | — | US | disclosed |
| US-8901336-B2 | Catalysts, methods of making catalysts, and methods of use | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901336-B2 | Catalysts, methods of making catalysts, and methods of use | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901336-B2 | Catalysts, methods of making catalysts, and methods of use | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-20130060056-A1 | CATALYSTS, METHODS OF MAKING CATALYSTS, AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130060056-A1 | CATALYSTS, METHODS OF MAKING CATALYSTS, AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130060056-A1 | CATALYSTS, METHODS OF MAKING CATALYSTS, AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20120022070-A1 | Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use | EMORY UNIVERSITY (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060056-A1 | CATALYSTS, METHODS OF MAKING CATALYSTS, AND METHODS OF USE | SOD1, CAT, APEX1 | GABRA1 4028/4885LMNA 1130/4885GABRG2 3910/4885 |
| US-10256419-B2 | Organic electroluminescent materials and devices | EML4, TYR, CPNE4 | GABRA1 2476/4885LMNA 2569/4885GABRG2 2279/4885 |
| US-20120022070-A1 | Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use | HSP90AB1, HSP90AA1, HSP90AB2P | GABRA1 4096/4885LMNA 3338/4885GABRG2 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.